{"id":17982,"date":"2023-10-17T13:26:09","date_gmt":"2023-10-17T11:26:09","guid":{"rendered":"https:\/\/mostakbalaldawaa.com\/?p=17982"},"modified":"2023-10-17T13:27:36","modified_gmt":"2023-10-17T11:27:36","slug":"%d9%84%d8%ac%d9%86%d8%a9-%d8%a7%d9%84%d9%85%d9%86%d8%aa%d8%ac%d8%a7%d8%aa-%d8%a7%d9%84%d8%b7%d8%a8%d9%8a%d8%a9-%d8%a7%d9%84%d8%a3%d9%88%d8%b1%d9%88%d8%a8%d9%8a%d8%a9-%d8%aa%d9%88%d8%b5%d9%8a-%d8%a8","status":"publish","type":"post","link":"https:\/\/mostakbalaldawaa.com\/?p=17982","title":{"rendered":"\u00ab\u0644\u062c\u0646\u0629 \u0627\u0644\u0645\u0646\u062a\u062c\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629\u00bb \u062a\u0648\u0635\u064a \u0628\u062a\u0631\u062e\u064a\u0635 \u0633\u0628\u0639\u0629 \u0623\u062f\u0648\u064a\u0629 \u062c\u062f\u064a\u062f\u0629"},"content":{"rendered":"<h4>\u00a0\u0623\u0648\u0635\u062a \u0644\u062c\u0646\u0629 \u0627\u0644\u0645\u0646\u062a\u062c\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0629 \u0644\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0628\u0634\u0631\u064a (CHMP) \u0627\u0644\u062a\u0627\u0628\u0639\u0629 \u0644\u0648\u0643\u0627\u0644\u0629 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629 \u0628\u0633\u0628\u0639\u0629 \u0623\u062f\u0648\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0644\u0644\u062a\u0631\u062e\u064a\u0635.<\/h4>\n<h4>\u0648\u062a\u0634\u0645\u0644 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 Elrexfio \u0645\u0646 \u0634\u0631\u0643\u0629 Pfizer \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0627\u064a\u0644\u0648\u0645\u0627 \u0627\u0644\u0645\u062a\u0639\u062f\u062f\u0629 \u0648Veozah \u0645\u0646 Astellas Pharma \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u062d\u0631\u0643\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0629 \u0625\u0644\u0649 \u0627\u0644\u0634\u062f\u064a\u062f\u0629 (VMS) \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0646\u0642\u0637\u0627\u0639 \u0627\u0644\u0637\u0645\u062b.<\/h4>\n<h4>Elrexfio (elranatamab) \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u0645\u064f\u0634\u062a\u0628\u0643 \u0644\u062e\u0644\u0627\u064a\u0627 CD3 T \u062b\u0646\u0627\u0626\u064a\u0629 \u0627\u0644\u062e\u0635\u0648\u0635\u064a\u0629 \u064a\u064f\u0639\u0637\u0649 \u062a\u062d\u062a \u0627\u0644\u062c\u0644\u062f \u0644\u0645\u0633\u062a\u0636\u062f \u0646\u0636\u0648\u062c \u0627\u0644\u062e\u0644\u0627\u064a\u0627 B. \u0645\u0646\u062d\u062a \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 (FDA) \u0645\u0648\u0627\u0641\u0642\u0629 \u0633\u0631\u064a\u0639\u0629 \u0639\u0644\u0649 \u0639\u0642\u0627\u0631 Elrexfio \u0641\u064a \u0623\u063a\u0633\u0637\u0633 \u0644\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u062a\u0644\u0642\u0648\u0627 \u0623\u0631\u0628\u0639\u0629 \u062e\u0637\u0648\u0637 \u0639\u0644\u0627\u062c\u064a\u0629 \u0633\u0627\u0628\u0642\u0629 \u0639\u0644\u0649 \u0627\u0644\u0623\u0642\u0644\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0645\u062b\u0628\u0637 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0632\u0648\u0645\u060c \u0648\u0639\u0627\u0645\u0644 \u062a\u0639\u062f\u064a\u0644 \u0627\u0644\u0645\u0646\u0627\u0639\u0629\u060c \u0648\u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0645\u0636\u0627\u062f \u0623\u062d\u0627\u062f\u064a \u0627\u0644\u0646\u0633\u064a\u0644\u0629 \u0627\u0644\u0645\u0636\u0627\u062f \u0644\u0640 CD38.<\/h4>\n<h4>\u00a0\u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u062a\u0635\u0644 \u0645\u0628\u064a\u0639\u0627\u062a Elrexfio \u0625\u0644\u0649 536 \u0645\u0644\u064a\u0648\u0646 \u062f\u0648\u0644\u0627\u0631 \u0628\u062d\u0644\u0648\u0644 \u0639\u0627\u0645 2029. \u0623\u062d\u062f \u0645\u0646\u0627\u0641\u0633\u064a\u0647\u0627 \u0641\u064a \u0627\u0644\u0633\u0648\u0642 \u0647\u0648 Talvey (talquetamab-tgvs)\u060c \u0627\u0644\u0630\u064a \u062a\u0633\u0648\u0642\u0647 \u0634\u0631\u0643\u0629 Janssen\u060c \u0648\u0627\u0644\u0630\u064a \u062a\u0645\u062a \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u064a\u0647 \u0643\u0639\u0644\u0627\u062c \u0645\u0646 \u0627\u0644\u062e\u0637 \u0627\u0644\u062e\u0627\u0645\u0633 \u0644\u0644\u0648\u0631\u0645 \u0627\u0644\u0646\u0642\u0648\u064a \u0627\u0644\u0645\u062a\u0639\u062f\u062f \u0627\u0644\u0627\u0646\u062a\u0643\u0627\u0633\/\u0627\u0644\u0645\u0642\u0627\u0648\u0645 \u0644\u0644\u0639\u0644\u0627\u062c \u0641\u064a \u0623\u063a\u0633\u0637\u0633. \u0648\u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u062a\u062d\u0642\u0642 Talvey \u0645\u0628\u064a\u0639\u0627\u062a \u0628\u0642\u064a\u0645\u0629 1.9 \u0645\u0644\u064a\u0627\u0631 \u062f\u0648\u0644\u0627\u0631 \u0628\u062d\u0644\u0648\u0644 \u0639\u0627\u0645 2029.<\/h4>\n<h4>\u064a\u0639\u062a\u0628\u0631 Veozah \u0645\u0646 Astellas Pharma \u0639\u0644\u0627\u062c\u064b\u0627 \u063a\u064a\u0631 \u0647\u0631\u0645\u0648\u0646\u064a \u0644\u062a\u0642\u0644\u064a\u0644 \u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u062f\u0648\u0631\u0629 \u0627\u0644\u0634\u0647\u0631\u064a\u0629 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0629 \u0625\u0644\u0649 \u0627\u0644\u0634\u062f\u064a\u062f\u0629 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0646\u0642\u0637\u0627\u0639 \u0627\u0644\u0637\u0645\u062b. \u064a\u0639\u0645\u0644 Veozah \u0639\u0646 \u0637\u0631\u064a\u0642 \u0645\u0646\u0639 \u0627\u0631\u062a\u0628\u0627\u0637 neurokinin B \u0628\u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0639\u0635\u0628\u064a\u0629 Kisspeptin\/neurokinin B\/dynorphin (KNDy)\u060c \u0645\u0645\u0627 \u064a\u0642\u0644\u0644 \u0645\u0646 \u0627\u0644\u0647\u0628\u0627\u062a \u0627\u0644\u0633\u0627\u062e\u0646\u0629 \u0648\u0627\u0644\u062a\u0639\u0631\u0642 \u0627\u0644\u0644\u064a\u0644\u064a \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0627\u0644\u062a\u0648\u0627\u0632\u0646 \u0641\u064a \u0645\u0646\u0637\u0642\u0629 \u0645\u0627 \u062a\u062d\u062a \u0627\u0644\u0645\u0647\u0627\u062f\u060c \u0627\u0644\u062a\u064a \u062a\u062a\u062d\u0643\u0645 \u0641\u064a \u062f\u0631\u062c\u0629 \u0627\u0644\u062d\u0631\u0627\u0631\u0629.<\/h4>\n<h4>\u0648\u0627\u0641\u0642\u062a \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0639\u0644\u0649 Veozah \u0641\u064a \u0645\u0627\u064a\u0648 2023\u060c \u0648\u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u062a\u0635\u0644 \u0627\u0644\u0645\u0628\u064a\u0639\u0627\u062a \u0625\u0644\u0649 2.5 \u0645\u0644\u064a\u0627\u0631 \u062f\u0648\u0644\u0627\u0631 \u0628\u062d\u0644\u0648\u0644 \u0639\u0627\u0645 2029. \u0648\u0641\u0642\u064b\u0627 \u0644\u0644\u062a\u0642\u0631\u064a\u0631 \u0627\u0644\u0645\u0627\u0644\u064a \u0644\u0644\u0631\u0628\u0639 \u0627\u0644\u0623\u0648\u0644 \u0645\u0646 \u0627\u0644\u0633\u0646\u0629 \u0627\u0644\u0645\u0627\u0644\u064a\u0629 2023 \u0644\u0634\u0631\u0643\u0629 Astellas\u060c \u0643\u0627\u0646\u062a \u0645\u0628\u064a\u0639\u0627\u062a Veozah \u0641\u064a \u0627\u0644\u0631\u0628\u0639 \u0627\u0644\u0623\u0648\u0644 \u0645\u062d\u062f\u0648\u062f\u0629\u060c \u062d\u064a\u062b \u0628\u0644\u063a\u062a 6 \u0645\u0644\u0627\u064a\u064a\u0646 \u064a\u0646 \u064a\u0627\u0628\u0627\u0646\u064a (40 \u0623\u0644\u0641 \u062f\u0648\u0644\u0627\u0631)\u060c \u0648\u0645\u0639 \u0630\u0644\u0643\u060c \u062a\u062a\u0648\u0642\u0639 Astellas \u0623\u0646 \u062a\u0635\u0644 \u0627\u0644\u0645\u0628\u064a\u0639\u0627\u062a \u0625\u0644\u0649 49 \u064a\u0646\u064b\u0627 \u064a\u0627\u0628\u0627\u0646\u064a\u064b\u0627. 3 \u0645\u0644\u064a\u0627\u0631 \u062f\u0648\u0644\u0627\u0631 (3.3 \u0645\u0644\u064a\u0627\u0631 \u062f\u0648\u0644\u0627\u0631) \u0648\u0641\u0642\u064b\u0627 \u0644\u062a\u0648\u0642\u0639\u0627\u062a\u0647\u0627 \u0644\u0644\u0639\u0627\u0645 \u0628\u0623\u0643\u0645\u0644\u0647.<\/h4>\n<h4>\u0645\u0646 \u0628\u064a\u0646 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0645\u0648\u0635\u0649 \u0628\u0647\u0627 \u0634\u0631\u0643\u0629 Agamree (\u0641\u0627\u0645\u0648\u0631\u0648\u0644\u0648\u0646) \u0645\u0646 \u0634\u0631\u0643\u0629 Santhera Pharmaceuticals \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062d\u062b\u0644 \u0627\u0644\u0639\u0636\u0644\u064a \u0627\u0644\u062f\u0648\u0634\u064a\u0646\u064a (DMD)\u060c \u0648Elucirem (\u062c\u0627\u062f\u0648\u0628\u064a\u0643\u0644\u064a\u0646\u0648\u0644) \u0645\u0646 \u0634\u0631\u0643\u0629 Geurbet\u060c \u0648Vueway (\u062c\u0627\u062f\u0648\u0628\u064a\u0643\u0644\u064a\u0646\u0648\u0644) \u0645\u0646 \u0634\u0631\u0643\u0629 Bracco Imaging\u060c \u0648\u0643\u0644\u0627\u0647\u0645\u0627 \u064a\u0633\u062a\u062e\u062f\u0645 \u0644\u062a\u0634\u062e\u064a\u0635 \u0627\u0644\u062a\u0635\u0648\u064a\u0631 \u0628\u0627\u0644\u0631\u0646\u064a\u0646 \u0627\u0644\u0645\u063a\u0646\u0627\u0637\u064a\u0633\u064a.<\/h4>\n<h4>\u0648\u062a\u0634\u0645\u0644 \u0627\u0644\u0642\u0627\u0626\u0645\u0629 \u0623\u064a\u0636\u064b\u0627 \u0639\u0642\u0627\u0631 Loargys (\u0628\u064a\u062c\u0632\u064a\u0644\u0627\u0631\u062c\u064a\u0646\u0627\u0632) \u0627\u0644\u0630\u064a \u062a\u0646\u062a\u062c\u0647 \u0634\u0631\u0643\u0629 \u0625\u064a\u0645\u062f\u064a\u0643\u0627 \u0641\u0627\u0631\u0645\u0627 \u0644\u0639\u0644\u0627\u062c \u0641\u0631\u0637 \u0623\u0631\u062c\u064a\u0646\u064a\u0646 \u0627\u0644\u062f\u0645\u060c \u0648\u0639\u0642\u0627\u0631 \u0631\u064a\u0632\u0627\u064a\u0648 (rezafungin)\u060c \u0627\u0644\u0630\u064a \u062a\u0633\u0648\u0642\u0647 \u0634\u0631\u0643\u0629 \u0645\u0648\u0646\u062f\u064a\u0641\u0627\u0631\u0645\u0627 \u0644\u0639\u0644\u0627\u062c \u062f\u0627\u0621 \u0627\u0644\u0645\u0628\u064a\u0636\u0627\u062a \u0627\u0644\u063a\u0627\u0632\u064a.<\/h4>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0\u0623\u0648\u0635\u062a \u0644\u062c\u0646\u0629 \u0627\u0644\u0645\u0646\u062a\u062c\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0629 \u0644\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0628\u0634\u0631\u064a (CHMP) \u0627\u0644\u062a\u0627\u0628\u0639\u0629 \u0644\u0648\u0643\u0627\u0644\u0629 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629 \u0628\u0633\u0628\u0639\u0629 \u0623\u062f\u0648\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0644\u0644\u062a\u0631\u062e\u064a\u0635. \u0648\u062a\u0634\u0645\u0644 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 Elrexfio \u0645\u0646 \u0634\u0631\u0643\u0629 Pfizer \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0627\u064a\u0644\u0648\u0645\u0627 \u0627\u0644\u0645\u062a\u0639\u062f\u062f\u0629 \u0648Veozah \u0645\u0646 Astellas Pharma \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u062d\u0631\u0643\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0629 \u0625\u0644\u0649 \u0627\u0644\u0634\u062f\u064a\u062f\u0629 (VMS) \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0646\u0642\u0637\u0627\u0639 \u0627\u0644\u0637\u0645\u062b. Elrexfio (elranatamab) \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u0645\u064f\u0634\u062a\u0628\u0643 \u0644\u062e\u0644\u0627\u064a\u0627 CD3 T \u062b\u0646\u0627\u0626\u064a\u0629 \u0627\u0644\u062e\u0635\u0648\u0635\u064a\u0629 \u064a\u064f\u0639\u0637\u0649 \u062a\u062d\u062a \u0627\u0644\u062c\u0644\u062f \u0644\u0645\u0633\u062a\u0636\u062f \u0646\u0636\u0648\u062c \u0627\u0644\u062e\u0644\u0627\u064a\u0627 &hellip;<\/p>\n","protected":false},"author":5,"featured_media":17983,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[106],"tags":[992,111,546],"class_list":["post-17982","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-106","tag-992","tag-111","tag-546"],"_links":{"self":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts\/17982","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17982"}],"version-history":[{"count":3,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts\/17982\/revisions"}],"predecessor-version":[{"id":17986,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts\/17982\/revisions\/17986"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/media\/17983"}],"wp:attachment":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17982"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17982"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17982"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}