{"id":18431,"date":"2023-10-29T14:15:18","date_gmt":"2023-10-29T12:15:18","guid":{"rendered":"https:\/\/mostakbalaldawaa.com\/?p=18431"},"modified":"2023-10-29T14:16:06","modified_gmt":"2023-10-29T12:16:06","slug":"%d9%87%d9%8a%d8%a6%d8%a9-%d8%a7%d9%84%d8%af%d9%88%d8%a7%d8%a1-%d8%a7%d9%84%d8%a3%d9%85%d8%b1%d9%8a%d9%83%d9%8a%d8%a9-%d8%aa%d9%88%d8%a7%d9%81%d9%82-%d8%b9%d9%84%d9%8a-%d8%b9%d9%82%d8%a7%d8%b1-14","status":"publish","type":"post","link":"https:\/\/mostakbalaldawaa.com\/?p=18431","title":{"rendered":"\u0647\u064a\u0626\u0629 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u062a\u0648\u0627\u0641\u0642 \u0639\u0644\u064a \u0639\u0642\u0627\u0631 \u00ab\u0623\u0648\u0645\u0641\u0648\u0647\u00bb \u0645\u0646 \u00ab\u0625\u064a\u0644\u064a \u0644\u064a\u0644\u064a\u00bb \u0644\u0639\u0644\u0627\u062c \u0625\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0642\u0648\u0644\u0648\u0646 \u0627\u0644\u062a\u0642\u0631\u062d\u064a"},"content":{"rendered":"

\u00a0\u062d\u0635\u0644 \u0639\u0642\u0627\u0631 Omvoh (mirikizumab) \u0645\u0646 \u0634\u0631\u0643\u0629 Eli Lilly \u0639\u0644\u0649 \u0645\u0648\u0627\u0641\u0642\u0629 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 (FDA) \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0642\u0648\u0644\u0648\u0646 \u0627\u0644\u062a\u0642\u0631\u062d\u064a \u0627\u0644\u0646\u0634\u0637 \u0627\u0644\u0645\u0639\u062a\u062f\u0644 \u0625\u0644\u0649 \u0627\u0644\u0634\u062f\u064a\u062f (UC) \u0644\u062f\u0649 \u0627\u0644\u0628\u0627\u0644\u063a\u064a\u0646 \u0628\u0639\u062f \u0631\u0641\u0636\u0647 \u0641\u064a \u0648\u0642\u062a \u0633\u0627\u0628\u0642 \u0645\u0646 \u0647\u0630\u0627 \u0627\u0644\u0639\u0627\u0645.<\/h4>\n

\u0641\u064a \u0623\u0628\u0631\u064a\u0644\u060c \u0631\u0641\u0636\u062a \u0627\u0644\u0648\u0643\u0627\u0644\u0629 \u0637\u0644\u0628 \u0627\u0644\u062a\u0631\u062e\u064a\u0635 \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a (BLA) \u0644\u0640 Omvoh \u0628\u0633\u0628\u0628 \u0645\u062e\u0627\u0648\u0641 \u0627\u0644\u062a\u0635\u0646\u064a\u0639. \u062a\u0645\u062a \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0636\u0627\u062f \u0644\u0644\u0625\u0646\u062a\u0631\u0644\u0648\u0643\u064a\u0646 (IL) -23 \u0644\u0639\u0644\u0627\u062c \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u0642\u0648\u0644\u0648\u0646 \u0648\u0627\u0644\u0645\u0633\u062a\u0642\u064a\u0645 \u0641\u064a \u0627\u0644\u064a\u0627\u0628\u0627\u0646 \u0648\u0627\u0644\u0627\u062a\u062d\u0627\u062f \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a.<\/h4>\n

UC \u0647\u0648 \u0646\u0648\u0639 \u0645\u0646 \u0645\u0631\u0636 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0623\u0645\u0639\u0627\u0621 \u0627\u0644\u0630\u064a \u064a\u0633\u0628\u0628 \u0623\u0639\u0631\u0627\u0636 \u0645\u062b\u0644 \u0627\u0644\u0625\u0633\u0647\u0627\u0644 \u0648\u0627\u0644\u0625\u0645\u0633\u0627\u0643. \u062a\u0645\u062a \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u0623\u062f\u0648\u064a\u0629 \u0645\u062a\u0639\u062f\u062f\u0629 \u0644\u0639\u0644\u0627\u062c \u0645\u0631\u0636 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0623\u0645\u0639\u0627\u0621.<\/h4>\n

\u0633\u062a\u0635\u0644 \u0634\u0631\u0643\u0629 Omvoh \u0625\u0644\u0649 \u0627\u0644\u0633\u0648\u0642 \u0627\u0644\u0630\u064a \u064a\u062a\u0645\u064a\u0632 \u0628\u0623\u062f\u0648\u064a\u0629 \u0631\u0627\u0633\u062e\u0629 \u0630\u0627\u062a \u0631\u0628\u062d\u064a\u0629 \u0639\u0627\u0644\u064a\u0629 \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0642\u0648\u0644\u0648\u0646 \u0627\u0644\u062a\u0642\u0631\u062d\u064a \u0645\u062b\u0644 Humira \u0645\u0646 AbbVie (adalimumab) \u0648Janssen’s Stelara (ustekinumab). \u0648\u062d\u0642\u0642\u062a \u0627\u0644\u0623\u062f\u0648\u064a\u0629 4 \u0645\u0644\u064a\u0627\u0631\u0627\u062a \u062f\u0648\u0644\u0627\u0631 \u06484.8 \u0645\u0644\u064a\u0627\u0631 \u062f\u0648\u0644\u0627\u0631 \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a \u0641\u064a \u0627\u0644\u0646\u0635\u0641 \u0627\u0644\u0623\u0648\u0644 \u0645\u0646 \u0639\u0627\u0645 2023\u060c \u0648\u0641\u0642\u064b\u0627 \u0644\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0645\u0627\u0644\u064a\u0629 \u0644\u0644\u0634\u0631\u0643\u0627\u062a \u0644\u0644\u0631\u0628\u0639 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0639\u0627\u0645 2023.<\/h4>\n

\u0634\u0647\u062f \u0647\u0630\u0627 \u0627\u0644\u0639\u0627\u0645 \u0648\u0635\u0648\u0644 \u0627\u0644\u0628\u062f\u0627\u0626\u0644 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 Humira \u0625\u0644\u0649 \u0627\u0644\u0633\u0648\u0642 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629\u060c \u0627\u0644\u0623\u0645\u0631 \u0627\u0644\u0630\u064a \u062a\u0633\u0628\u0628 \u0628\u0627\u0644\u0641\u0639\u0644 \u0641\u064a \u0627\u0646\u062e\u0641\u0627\u0636 \u0623\u0631\u0628\u0627\u062d \u0634\u0631\u0643\u0629 AbbVie. \u0623\u0639\u0644\u0646\u062a \u0627\u0644\u0634\u0631\u0643\u0629 \u0639\u0646 \u0627\u0646\u062e\u0641\u0627\u0636 \u0628\u0646\u0633\u0628\u0629 26% \u064819.8% \u0641\u064a \u0625\u064a\u0631\u0627\u062f\u0627\u062a \u0634\u0631\u0643\u0629 Humira \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0648\u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 \u0644\u0644\u0646\u0635\u0641 \u0627\u0644\u0623\u0648\u0644 \u0645\u0646 \u0639\u0627\u0645 2023\u060c \u0648\u0641\u0642\u064b\u0627 \u0644\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0645\u0627\u0644\u064a\u0629 \u0644\u0644\u0634\u0631\u0643\u0629 \u0644\u0644\u0631\u0628\u0639 \u0627\u0644\u062b\u0627\u0646\u064a \u0645\u0646 \u0639\u0627\u0645 2023.<\/h4>\n

\u0648\u062a\u062a\u0648\u0642\u0639 \u0627\u0644\u0634\u0631\u0643\u0629 \u0623\u0646 \u062a\u062d\u0642\u0642 Omvoh \u0645\u0628\u064a\u0639\u0627\u062a \u0639\u0627\u0644\u0645\u064a\u0629 \u0628\u0642\u064a\u0645\u0629 1.2 \u0645\u0644\u064a\u0627\u0631 \u062f\u0648\u0644\u0627\u0631 \u0641\u064a \u0639\u0627\u0645 2029.<\/h4>\n

\u0627\u0639\u062a\u0645\u062f\u062a \u0645\u0648\u0627\u0641\u0642\u0629 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 (FDA) \u0639\u0644\u0649 \u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629 \u0645\u0646 LUCENT (NCT03518086 \u0648NCT03524092) \u0641\u064a \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0642\u0648\u0644\u0648\u0646 \u0627\u0644\u062a\u0642\u0631\u062d\u064a \u0648\u0627\u0644\u0630\u064a\u0646 \u062a\u0644\u0642\u0648\u0627 \u0639\u0644\u0627\u062c\u064b\u0627 \u0645\u0633\u0628\u0642\u064b\u0627. \u062d\u0642\u0642 \u0645\u0627 \u064a\u0642\u0631\u0628 \u0645\u0646 65% \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0633\u0631\u064a\u0631\u064a\u0629\u060c \u0648\u0623\u0638\u0647\u0631 24% \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0647\u062f\u0623\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0648\u0647\u0645\u064a \u0628\u0639\u062f 12 \u0623\u0633\u0628\u0648\u0639\u064b\u0627 \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c.<\/h4>\n

\u00a0\u0643\u0645\u0627 \u0623\u062f\u0649 \u0627\u0644\u0639\u0644\u0627\u062c \u0623\u0645\u0641\u0648\u0647 \u0625\u0644\u0649 \u062a\u062d\u0633\u064a\u0646 \u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0642\u0648\u0644\u0648\u0646 \u0627\u0644\u062a\u0642\u0631\u062d\u064a \u0645\u062b\u0644 \u0646\u0632\u064a\u0641 \u0627\u0644\u0645\u0633\u062a\u0642\u064a\u0645 \u0648\u062a\u0643\u0631\u0627\u0631 \u0627\u0644\u0628\u0631\u0627\u0632. \u062a\u0634\u0645\u0644 \u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629 \u0627\u0644\u0634\u0627\u0626\u0639\u0629 \u0627\u0644\u062a\u064a \u0644\u0648\u062d\u0638\u062a \u0645\u0639 Omvoh \u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u062a\u0646\u0641\u0633\u064a \u0627\u0644\u0639\u0644\u0648\u064a\u060c \u0648\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0645\u0648\u0642\u0639 \u0627\u0644\u062d\u0642\u0646\u060c \u0648\u0627\u0644\u0639\u062f\u0648\u0649 \u0627\u0644\u0641\u064a\u0631\u0648\u0633\u064a\u0629 \u0628\u0627\u0644\u0647\u0631\u0628\u0633.<\/h4>\n

\u062a\u0634\u0645\u0644 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0627\u062a \u0627\u0644\u062c\u062f\u064a\u062f\u0629 \u0627\u0644\u0623\u062e\u0631\u0649 \u0644\u0639\u0644\u0627\u062c UC \u0645\u0648\u0627\u0641\u0642\u0629 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0639\u0644\u0649 \u0639\u0642\u0627\u0631 Pfizer\u2019s Velsipity (etasimod)\u060c \u0648\u0647\u0648 \u0645\u064f\u0639\u062f\u0650\u0651\u0644 \u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a sphingosine-1-phosphate (S1P) \u0627\u0644\u0627\u0646\u062a\u0642\u0627\u0626\u064a \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0641\u0645 \u0645\u0631\u0629 \u0648\u0627\u062d\u062f\u0629 \u064a\u0648\u0645\u064a\u064b\u0627.<\/h4>\n","protected":false},"excerpt":{"rendered":"

\u00a0\u062d\u0635\u0644 \u0639\u0642\u0627\u0631 Omvoh (mirikizumab) \u0645\u0646 \u0634\u0631\u0643\u0629 Eli Lilly \u0639\u0644\u0649 \u0645\u0648\u0627\u0641\u0642\u0629 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 (FDA) \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0642\u0648\u0644\u0648\u0646 \u0627\u0644\u062a\u0642\u0631\u062d\u064a \u0627\u0644\u0646\u0634\u0637 \u0627\u0644\u0645\u0639\u062a\u062f\u0644 \u0625\u0644\u0649 \u0627\u0644\u0634\u062f\u064a\u062f (UC) \u0644\u062f\u0649 \u0627\u0644\u0628\u0627\u0644\u063a\u064a\u0646 \u0628\u0639\u062f \u0631\u0641\u0636\u0647 \u0641\u064a \u0648\u0642\u062a \u0633\u0627\u0628\u0642 \u0645\u0646 \u0647\u0630\u0627 \u0627\u0644\u0639\u0627\u0645. \u0641\u064a \u0623\u0628\u0631\u064a\u0644\u060c \u0631\u0641\u0636\u062a \u0627\u0644\u0648\u0643\u0627\u0644\u0629 \u0637\u0644\u0628 \u0627\u0644\u062a\u0631\u062e\u064a\u0635 \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a (BLA) \u0644\u0640 Omvoh \u0628\u0633\u0628\u0628 \u0645\u062e\u0627\u0648\u0641 \u0627\u0644\u062a\u0635\u0646\u064a\u0639. \u062a\u0645\u062a \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0636\u0627\u062f \u0644\u0644\u0625\u0646\u062a\u0631\u0644\u0648\u0643\u064a\u0646 (IL) -23 …<\/p>\n","protected":false},"author":5,"featured_media":17352,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[106],"tags":[1206,1117,111,284],"class_list":["post-18431","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-106","tag-1206","tag-1117","tag-111","tag-284"],"_links":{"self":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts\/18431","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18431"}],"version-history":[{"count":2,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts\/18431\/revisions"}],"predecessor-version":[{"id":18433,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts\/18431\/revisions\/18433"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/media\/17352"}],"wp:attachment":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18431"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18431"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18431"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}