{"id":61828,"date":"2024-09-19T14:52:40","date_gmt":"2024-09-19T12:52:40","guid":{"rendered":"https:\/\/mostakbalaldawaa.com\/?p=61828"},"modified":"2024-09-19T14:52:40","modified_gmt":"2024-09-19T12:52:40","slug":"%d9%87%d9%8a%d8%a6%d8%a9-%d8%a7%d9%84%d8%af%d9%88%d8%a7%d8%a1-%d8%a7%d9%84%d8%a3%d9%85%d8%b1%d9%8a%d9%83%d9%8a%d8%a9-%d8%aa%d9%88%d8%a7%d9%81%d9%82-%d8%b9%d9%84%d9%8a-%d9%85%d8%ac%d9%85%d9%88%d8%b9-3","status":"publish","type":"post","link":"https:\/\/mostakbalaldawaa.com\/?p=61828","title":{"rendered":"\u0647\u064a\u0626\u0629 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u062a\u0648\u0627\u0641\u0642 \u0639\u0644\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u00ab\u0643\u064a\u062a\u0631\u0648\u062f\u0627\u00bb \u0645\u0646 \u00ab\u0645\u064a\u0631\u0643\u00bb \u0644\u0639\u0644\u0627\u062c \u0648\u0631\u0645 \u0627\u0644\u0638\u0647\u0627\u0631\u0629 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0629 \u0627\u0644\u062c\u0646\u0628\u064a"},"content":{"rendered":"
\u00a0\u0648\u0627\u0641\u0642\u062a \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 (FDA) \u0639\u0644\u0649 \u0646\u0638\u0627\u0645 KEYTRUDA \u0645\u0646 MSD \u0643\u0639\u0644\u0627\u062c \u0627\u0644\u062e\u0637 \u0627\u0644\u0623\u0648\u0644 \u0644\u0644\u0628\u0627\u0644\u063a\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0648\u0631\u0645 \u0627\u0644\u0638\u0647\u0627\u0631\u0629 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0629 \u0627\u0644\u062c\u0646\u0628\u064a \u0627\u0644\u062e\u0628\u064a\u062b \u0627\u0644\u0645\u062a\u0642\u062f\u0645 \u0623\u0648 \u0627\u0644\u0646\u0642\u064a\u0644\u064a (MPM).<\/h5>\n

\n

\u0639\u0644\u0627\u062c \u0645\u0636\u0627\u062f \u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u0645\u0628\u0631\u0645\u062c\u0629 -1 (PD-1)\u060c \u064a\u0634\u0627\u0631 \u0625\u0644\u0649 \u0627\u0644\u0639\u0644\u0627\u062c \u0644\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0639 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0628\u064a\u0645\u064a\u062a\u0631\u064a\u0643\u0633\u064a\u062f \u0648\u0627\u0644\u0628\u0644\u0627\u062a\u064a\u0646.<\/p>\n

\u064a\u062a\u0645 \u062f\u0639\u0645 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u0646\u0638\u0627\u0645 KEYTRUDA \u0645\u0646 \u062e\u0644\u0627\u0644 \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629\/\u0627\u0644\u062b\u0627\u0644\u062b\u0629 \u0645\u0646 \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 IND.227\/KEYNOTE-483.<\/p>\n

\n\u0643\u0627\u0646\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u062c\u0647\u062f \u062a\u0639\u0627\u0648\u0646\u064a \u064a\u0636\u0645 CCTG \u0648Intergroupe Francophone de Canc\u00e9rologie Thoracique \u0648\u0627\u0644\u0645\u0639\u0647\u062f \u0627\u0644\u0648\u0637\u0646\u064a \u0644\u0644\u0633\u0631\u0637\u0627\u0646 \u0641\u064a \u0646\u0627\u0628\u0648\u0644\u064a.<\/p>\n

\u0642\u062f\u0645\u062a \u0634\u0631\u0643\u0629 MSD \u0627\u0644\u062f\u0648\u0627\u0621 \u0648\u0627\u0644\u062f\u0639\u0645 \u0627\u0644\u0625\u0636\u0627\u0641\u064a \u0644\u0644\u062a\u062c\u0631\u0628\u0629.<\/p>\n

\n\u0642\u0627\u0645 \u0627\u0644\u062c\u0632\u0621 \u0627\u0644\u062b\u0627\u0644\u062b \u0645\u0646 \u062a\u062c\u0631\u0628\u0629 IND.227\/KEYNOTE-483 \u0628\u062a\u0633\u062c\u064a\u0644 440 \u0645\u0631\u064a\u0636\u064b\u0627 \u0644\u0645 \u064a\u062a\u0644\u0642\u0648\u0627 \u0639\u0644\u0627\u062c\u064b\u0627 \u062c\u0647\u0627\u0632\u064a\u064b\u0627 \u0645\u0633\u0628\u0642\u064b\u0627 \u0644\u0645\u0631\u0636 MPM \u0627\u0644\u0645\u062a\u0642\u062f\u0645 \u0644\u062f\u064a\u0647\u0645.<\/p>\n

\u062a\u0645 \u0627\u062e\u062a\u064a\u0627\u0631 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0628\u0634\u0643\u0644 \u0639\u0634\u0648\u0627\u0626\u064a \u0644\u062a\u0644\u0642\u064a KEYTRUDA \u0645\u0639 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0623\u0648 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0648\u062d\u062f\u0647\u060c \u0645\u0639 \u0625\u0639\u0637\u0627\u0621 \u062c\u0645\u064a\u0639 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u062a\u0633\u0631\u064a\u0628 \u0641\u064a \u0627\u0644\u0648\u0631\u064a\u062f.<\/p>\n

\u0623\u062f\u0649 \u0647\u0630\u0627 \u0627\u0644\u0645\u0632\u064a\u062c \u0625\u0644\u0649 \u062a\u062d\u0633\u0646 \u0645\u0644\u062d\u0648\u0638 \u0625\u062d\u0635\u0627\u0626\u064a\u064b\u0627 \u0641\u064a \u0625\u062c\u0645\u0627\u0644\u064a \u0627\u0644\u0628\u0642\u0627\u0621 \u0639\u0644\u0649 \u0642\u064a\u062f \u0627\u0644\u062d\u064a\u0627\u0629 (OS)\u060c \u0645\u0639 \u0627\u0646\u062e\u0641\u0627\u0636 \u0645\u0639\u062f\u0644 \u0627\u0644\u0648\u0641\u064a\u0627\u062a \u0628\u0646\u0633\u0628\u0629 21\u066a \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0648\u062d\u062f\u0647.<\/p>\n

\n\u062a\u0645 \u0627\u0644\u0625\u0628\u0644\u0627\u063a \u0639\u0646 \u0623\u0646 \u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u200b\u200b\u0646\u0638\u0627\u0645 \u0627\u0644\u062a\u0634\u063a\u064a\u0644 \u064a\u0628\u0644\u063a 17.3 \u0634\u0647\u0631\u064b\u0627 \u0644\u0644\u0645\u0631\u0636\u0649 \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 KEYTRUDA \u0645\u0642\u0627\u0628\u0644 16.1 \u0634\u0647\u0631\u064b\u0627 \u0644\u0623\u0648\u0644\u0626\u0643 \u0627\u0644\u0630\u064a\u0646 \u064a\u062a\u0644\u0642\u0648\u0646 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0648\u062d\u062f\u0647.<\/p>\n

\u0623\u0638\u0647\u0631 KEYTRUDA \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0623\u064a\u0636\u064b\u0627 \u062a\u062d\u0633\u0646\u064b\u0627 \u0643\u0628\u064a\u0631\u064b\u0627 \u0641\u064a \u0627\u0644\u0628\u0642\u0627\u0621 \u0639\u0644\u0649 \u0642\u064a\u062f \u0627\u0644\u062d\u064a\u0627\u0629 \u0628\u062f\u0648\u0646 \u062a\u0642\u062f\u0645 \u0627\u0644\u0645\u0631\u0636 \u0648\u0645\u0639\u062f\u0644 \u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u0625\u062c\u0645\u0627\u0644\u064a \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0648\u062d\u062f\u0647.<\/p>\n

\u062a\u0645 \u0627\u0644\u0639\u062b\u0648\u0631 \u0639\u0644\u0649 \u0645\u0644\u0641 \u0633\u0644\u0627\u0645\u0629 KEYTRUDA \u0641\u064a \u0645\u0631\u0636\u0649 MPM \u064a\u062a\u0645\u0627\u0634\u0649 \u0645\u0639 \u062a\u0644\u0643 \u0627\u0644\u062a\u064a \u0644\u0648\u062d\u0638\u062a \u0641\u064a \u0623\u0646\u0648\u0627\u0639 \u0627\u0644\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u0623\u062e\u0631\u0649 \u0639\u0646\u062f \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0647\u0627 \u0628\u0627\u0644\u062a\u0632\u0627\u0645\u0646 \u0645\u0639 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0628\u064a\u0645\u064a\u062a\u0631\u064a\u0643\u0633\u064a\u062f \u0648\u0627\u0644\u0628\u0644\u0627\u062a\u064a\u0646.<\/p>\n

\u0648\u0647\u0648 \u064a\u0639\u0645\u0644 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0645\u0646\u0639 \u0627\u0644\u062a\u0641\u0627\u0639\u0644 \u0628\u064a\u0646 PD-1 \u0648\u0631\u0648\u0627\u0628\u0637\u0647\u060c PD-L1 \u0648PD-L2\u060c \u0645\u0645\u0627 \u064a\u0624\u062f\u064a \u0625\u0644\u0649 \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0644\u064a\u0645\u0641\u0627\u0648\u064a\u0629 \u0627\u0644\u062a\u0627\u0626\u064a\u0629 \u0644\u0627\u0643\u062a\u0634\u0627\u0641 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0633\u0631\u0637\u0627\u0646\u064a\u0629 \u0648\u0645\u0643\u0627\u0641\u062d\u062a\u0647\u0627.<\/p>\n

\u0635\u0631\u062d \u0646\u0627\u0626\u0628 \u0631\u0626\u064a\u0633 \u0627\u0644\u0623\u0628\u062d\u0627\u062b \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u0644\u0623\u0648\u0631\u0627\u0645 \u0641\u064a Merck Research Laboratories\u060c \u0627\u0644\u062f\u0643\u062a\u0648\u0631 \u063a\u0631\u064a\u063a\u0648\u0631\u064a \u0644\u0648\u0628\u064a\u0646\u064a\u0643\u064a: “\u064a\u0633\u0639\u062f\u0646\u0627 \u0623\u0646 \u0646\u0642\u062f\u0645 \u062e\u064a\u0627\u0631 \u0639\u0644\u0627\u062c \u0627\u0644\u062e\u0637 \u0627\u0644\u0623\u0648\u0644 \u0627\u0644\u062c\u062f\u064a\u062f \u0644\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0628\u0627\u0644\u063a\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0648\u0631\u0645 \u0627\u0644\u0638\u0647\u0627\u0631\u0629 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0629 \u0627\u0644\u062c\u0646\u0628\u064a \u0627\u0644\u062e\u0628\u064a\u062b \u0627\u0644\u0645\u062a\u0642\u062f\u0645 \u0623\u0648 \u0627\u0644\u0646\u0642\u064a\u0644\u064a \u063a\u064a\u0631 \u0627\u0644\u0642\u0627\u0628\u0644 \u0644\u0644\u0627\u0633\u062a\u0626\u0635\u0627\u0644\u060c \u0648\u0647\u0648 \u0645\u0631\u0636 \u062a\u0643\u0648\u0646 \u0627\u0644\u062a\u0634\u062e\u064a\u0635\u0627\u062a \u0641\u064a\u0647 \u0633\u064a\u0626\u0629 \u0628\u0634\u0643\u0644 \u0639\u0627\u0645.<\/p>\n

“\u064a\u0624\u0643\u062f \u0647\u0630\u0627 \u0627\u0644\u0625\u0646\u062c\u0627\u0632 \u0627\u0644\u0628\u0627\u0631\u0632 \u0627\u0644\u062a\u0632\u0627\u0645\u0646\u0627 \u0628\u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0623\u0628\u062d\u0627\u062b \u0644\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0623\u0648\u0631\u0627\u0645 \u064a\u0635\u0639\u0628 \u0639\u0644\u0627\u062c\u0647\u0627.”<\/p>\n

\u0641\u064a \u064a\u0648\u0644\u064a\u0648 2024\u060c \u0627\u0633\u062a\u062d\u0648\u0630\u062a MSD \u0639\u0644\u0649 Eyebiotech (EyeBio) \u0641\u064a \u0635\u0641\u0642\u0629 \u0628\u0644\u063a\u062a \u0642\u064a\u0645\u062a\u0647\u0627 \u0627\u0644\u0625\u062c\u0645\u0627\u0644\u064a\u0629 1.3 \u0645\u0644\u064a\u0627\u0631 \u062f\u0648\u0644\u0627\u0631\u060c \u0645\u0645\u0627 \u062c\u0639\u0644 \u0627\u0644\u0634\u0631\u0643\u0629 \u062a\u0627\u0628\u0639\u0629 \u0644\u0647\u0627.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u00a0\u0648\u0627\u0641\u0642\u062a \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 (FDA) \u0639\u0644\u0649 \u0646\u0638\u0627\u0645 KEYTRUDA \u0645\u0646 MSD \u0643\u0639\u0644\u0627\u062c \u0627\u0644\u062e\u0637 \u0627\u0644\u0623\u0648\u0644 \u0644\u0644\u0628\u0627\u0644\u063a\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0648\u0631\u0645 \u0627\u0644\u0638\u0647\u0627\u0631\u0629 \u0627\u0644\u0645\u062a\u0648\u0633\u0637\u0629 \u0627\u0644\u062c\u0646\u0628\u064a \u0627\u0644\u062e\u0628\u064a\u062b \u0627\u0644\u0645\u062a\u0642\u062f\u0645 \u0623\u0648 \u0627\u0644\u0646\u0642\u064a\u0644\u064a (MPM). \u0639\u0644\u0627\u062c \u0645\u0636\u0627\u062f \u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u0627\u0644\u0645\u0648\u062a \u0627\u0644\u0645\u0628\u0631\u0645\u062c\u0629 -1 (PD-1)\u060c \u064a\u0634\u0627\u0631 \u0625\u0644\u0649 \u0627\u0644\u0639\u0644\u0627\u062c \u0644\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0645\u0639 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0628\u064a\u0645\u064a\u062a\u0631\u064a\u0643\u0633\u064a\u062f \u0648\u0627\u0644\u0628\u0644\u0627\u062a\u064a\u0646. \u064a\u062a\u0645 \u062f\u0639\u0645 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u0646\u0638\u0627\u0645 KEYTRUDA \u0645\u0646 \u062e\u0644\u0627\u0644 \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629\/\u0627\u0644\u062b\u0627\u0644\u062b\u0629 \u0645\u0646 …<\/p>\n","protected":false},"author":5,"featured_media":60507,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[106],"tags":[211,2852,111,284],"class_list":["post-61828","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-106","tag-211","tag-2852","tag-111","tag-284"],"_links":{"self":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts\/61828","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=61828"}],"version-history":[{"count":1,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts\/61828\/revisions"}],"predecessor-version":[{"id":61829,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/posts\/61828\/revisions\/61829"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=\/wp\/v2\/media\/60507"}],"wp:attachment":[{"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=61828"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=61828"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mostakbalaldawaa.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=61828"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}